Global overview _ general knowledge of asthma at present

Global overview _ general knowledge of asthma at present
The global asthma morbidity is rising, especially children's morbidity. According to prevention from suffering from the diseases and data of the control centre, nearly 5 million children in U.S.A. are made a definite diagnosis of and suffer from asthma. Though has taken positive research and precautionary measures, within 1980-1993 years, American children's mortality correlated to asthma has still risen by 78%. The situations of other countries are terrible equally too: There is one and is made a definite diagnosis of every 4 children in Australia and suffer from asthma; The ill rate of Israeli children's asthma has already doubled, has exceeded 11%; The ill rate of asthma of children of Costa Rica, Panama, Brazil, Peru, Uruguay is higher than 20%.
To epidemiologist, asthma is a thorny difficult problem. Every the intersection of area and the intersection of asthma and ill difference of rate, economic situation, nutritional status, race form and folkways and customs have something to do. Obscurely, the chance that the person of the developed country suffers from asthma is larger than that of the poor country.
To some asthma patients, it is ubiquitous to touch off the factor, and unable to avoid. The common factor that initiates asthma to break out includes car exhaust, cigarette smog, cold air, pollen and mould spore. Other "anaphylactogen which cause asthma include the toxin of bacterium, saliva of cockroach and excrement and urine. It will cause the disease to send while getting warm or cooking to use the firewood, coal, or coal gas indoors. This disease still demonstrates the family, though its mechanism is still indeterminate.
Global asthma and overview asthma are a kind of world disease. Study its morbidity in crowds of different areas of the world, for example Mexico and Wuhan, it contribute to it confirm about factors and those genetic last environmental factor and asthma relation during rates ill of gene expression. For example, ozone level of Mexico occupies the first place in North America continent, this may interact with the local crowd's characterized gene, make children exchange asthma of sense.
Totally understand asthma, must analyze all above-mentioned factors, in order to find out the each and common and pathogenic mechanism in the forming process of this disease of these factor. NIEHS (U.S.A. environmental sanitation research institute) The senior researcher Stephanie London of research department of epidemiology is in the inherent cause of research and interaction in the course of causing the asthma of the environmental factor.
One of the focal points that London studies is to demonstrate route and reason of different ill rate in different crowds through studying this disease, to announce the cause of asthma. It is initial to study, she begins from the influence emerging to a group children in California southern areas healthily in air pollution of the follow-up study, California the intersection of southern areas and the intersection of asthma and ill rate than high (as most areas of U.S.A.) . She increased the influence of the inherent cause in this research later. At present, London, to Wuhan of China (the ill rate of asthma is low) With the intersection of Mexico and children (ill to lead high than China, but still is lower than U.S.A.) of city Carry on research, and known asthma inspire function that factor's exposing to complicated pathogenic course of this disease blow by way of clarifying life.
Relation between asthma and ozone
London present working core is that exploration ozone carried on in Mexico is exposed with asthma several items of the relation are studied. London does not think ozone is the basic reason which initiates asthma. On the contrary, she regards ozone as one of the several possible latencies --Ozone of the children in Mexico exposes competence extremely tallly.
Ozone is a kind of very active shape of oxygen element, there is relatively low competence in the clean surrounding air naturally. But at the temperature, sunshine and fuel waste gas at the time of hydrocarbon comprehensive function, will rise to a dangerous density level. Because its serious air pollution and higher elevation, ozone level of Mexico is the top in North America. In 1995, the average atmospheric ozone density of Mexico was 0.15 ppm, and nearly twice of the daily highest average density which American Environmental Protection Agency stipulates at present.
At present, London is recruiting one batch in the children who suffers from asthma and a control group of 6-13 years old. The distinctive quality of this research lies in the research object not merely includes children, and include children's parents both sides. Form a research object in this way " Three people's group " ,Not only can study the inherent cause of asthma can study its environmental inducement but also.
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