What _'s treatments does effective therapeutic hepatitis B medicine have at present

What _'s treatments does effective therapeutic hepatitis B medicine have at present
Which are effective resisting the virus medicine of hepatitis B at present? How to choose to use medicine? Chronic hepatitis B treats the new development 1.Treat the goal: Duplicate or dispel infecting in order to prevent liver pathological change from developing through inhibiting hepatitis B and virus, embodied in: Serum HBVDNA is negative; Serum HBeAg negative, resist - HBe positive (" the big 3 north " Transfer to " three little male genital " ); Serum ALT is normal; Liver histology is improved. 2.Antiviral therapeutic indication: Serum HBVDNA and/or HBeAg is positive to last more than 6 months; Serum ALT level rises repeatedly; Check, brief hepatitis B and virus on chronically, infect by liver histology, there is intermediate more than inflammatory intensity. 3.Resist the virus medicine of hepatitis B effectively: 3.1a - interferon: 1992, American food and medicines administration bureau (FDA) Sanction a - interferon and is applied to treating the chronic hepatitis B patient, inhibits the virus from duplicating and inhibits the immunity from strengthening the function, recommend the dosage as 5 million units for each hypodermic injection, 3 times every week, the course of treatment and at least 6 months. This kind of medicine imports medicines at present " Can interfere with " , " Luo winds plainly " , " good fortune benevolence of the favor " And the domestic medicine " Have a match like gold " , " it is plain to transport Germany " , " Anda is fragrant " , " specially fragrant " When. Better index of curative effect includes: Level, HBVDNA of serum, lower than 200pg/mL treat, serum ALT in 100U/L above, liver histology checked and briefed the obvious inflammatory activity on, women, there is acute hepatitis history in the medical history, the virus infects time shorter continuously, it is not the mother-to-baby transmission, it is not the virus that makes a variation. Perhaps the bad reaction is as follows, cold is one kind of symptoms, the bone marrow is inhibited from (shown as the peripheral blood leucocyte counting, blood platelet is counted and dropped) ,The appetite fails, become thin, depilate, mental depression,etc.. 3.2 the intersection of Lammi and husband make: The intersection of Lammi and husband make (the goods of our country are called " He PuDing " )U.S.A. FDA sanctioned being applied to treating another kind of medicine of hepatitis B and virus in December of 1998, inhibit virus from duplicate function only, recommend healing solution as oral 100mg each time, 1 times a day, at least one year of course of treatment. Possible bad reaction: Have not found the obvious bad reaction yet at present. Notes: Treat for 9 months, need to check the virus and make a variation, prevent being able to bear the medicine situation to take place 3.3 suffused with the intersection of Lip river and Wei for less than former times: Suffused with the intersection of Lip river and Wei (goods are called for less than former times " The beautiful pearl wind " )Another the intersection of nucleoside and analog, function mechanism similar to the intersection of Lammi and, definitely, recommend scheme as oral 0.5g each time, 3 times a day, at least 4 months of course of treatment. 3.4 immune modulator: Thymic peptide a1 (the goods are called " Japan reaches the celestial being " )Strengthen pharmaceuticals for the immunity, play an antiviral role through strengthening the immune function on hepatitis B and virus, generally the unites application definitely, recommend the scheme as each hypodermic injection 1.6mg with a - interferon or Lammi, 1 times a day, change into every week 2 times 4 days later continuously, course of treatment is 4-6 months. 4.Notes: Monitor serum ALT, HBVDNA, HBeAg resist during the treatment period - HBe, treats under the guidance of professional doctor
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