Friday, July 6, 2012

Make what check the intersection of _ and general knowledge at the hepatocarcinoma

Make what check the intersection of _ and general knowledge at the hepatocarcinoma
It is primary continuing twoing of sending etc. for hepatocarcinoma to divide into, original, source, too, where it is that cancer take place, cancer is taken place at first by the liver, is called primary hepatocarcinoma; Shift to liver from other position of health, ask, continue taking place hepatocarcinoma. The fen type on pathology of hepatocarcinoma: Soaking type: To the intersection of cancer and component present the intersection of pseudopodium and kind, grow or and small the intersection of leaf and replacing growth false, it is apt to form the phlebangioma bolt of the door; Swelling type: Have the intersection of bag and membrane, to whether the intersection of cancer and position present, extrude kinds of dilated growth, tumour have next door in the tubercle, every organization type is unanimous; Phenotype: Change toward soaking type from the swelling type or both coexist. Organize the credit as the hepatocyte type: See more, account for 80%- 90%; Bile duct cells type: Relatively rare, develop slowly, the course of disease is relatively long, the prognosis is better; Phenotype: Relatively rare. Shift the route: Until blood competent to shift, take place initially, not most common in the liver, infringe portal vein, form the intersection of tumour and bolt, it causes the occuring frequently transformation cooking stove in the liver that the tumour bolt is lossed, through the blood one, lymphocytic way and planting shifting more outside the liver, person who shift most high with lung, secondly for bone and brain, kidney, lymph node,etc. shift at being clavicular. If suspect hepatocarcinoma, can do the following inspection:
(1) Check 1, liver function inspection in blood biochemistry: The hepatocarcinoma patient should act as liver function, check, the majority is normal, with can damage liver function at the time of liver cirrhosising, some patient serum GPT is high, hepatocarcinoma causes liver function to damage rarely seen to the later period patiently. 2,The tumour mark is checked (1) First child albumen (AFP) : It is a specific tumour mark which diagnoses the primary hepatocarcinoma, establish diagnosing, early diagnosis, function of differential diagnosis. Daily enzyme marks law, enzyme and marks the electric swimming law, radiates vaccinating to measure at present. Especially employ the diagnosis of the inferior clinical hepatocarcinoma in early days and perform the operation and can raise the patient's survival rate greatly in time. Judge, determine dynamically to curative effect and prognosis such as hepatocarcinoma surgery, chemotherapy, therapy of combining traditional Chinese and Western medicine, radiotherapy the child albumen of serum first has clinical value with important it. ( 2) Ferritin of serum (SF) : It is the second serological mark of the primary hepatocarcinoma, density of the ferritin of serum and intensity that the hepatocyte damages, whether liver cirrhosis exists or not, storing amount of the liver iron and liver tumour is relevant in size. Literature report serum ferritin diagnose primary the intersection of hepatocarcinoma and positive rate 50.8%- 88% , If first child albumen and serum ferritin jointly determine, any is positive as diagnosing the positive rate of the index reaches 92.1%, and the intersection of serum and ferritin determine quite meaningful when being negative in first the intersection of child and the intersection of albumen and low density especially, so serum ferritin and first the intersection of child and the intersection of albumen and integrated application improve primary person who diagnose in early days of hepatocarcinoma further. 3,Serum is determined (1), alkaline phosphatase: Serum alkaline phosphatase of hepatocarcinoma patient increase more, positive rate is 65%, exceed gold? A there is no jaundice to appear when the unit, or there is obstructive jaundice but alkaline phosphatase increases proportionally, brief on the possibility of hepatocarcinoma. (2), r a valley ammonia acyl is transferred to peptide enzyme (r - GT) : Patient's positive rate of hepatocarcinoma is 84.2% - 91.2%, the increasing of this enzyme may mainly come from tumour. (3), isoenzyme: There is deaminase (LDH) lactic acid in the determination of isoenzyme LDH5 vigor increases when isoenzyme is determined, primary hepatocarcinoma.
(2) It is a main means to diagnose primary hepatocarcinoma to study and check 1, supersonic wave to check in image, Ultrasonography B it adopts ultrasonic fault to be apparent to look like, show as, have, reflect luminous point, the intersection of cancer and the intersection of tumour and getting real dark district that roll, bring only only obviously around at the the intersection of audiovideo and picture. It is relatively high, there is certain value on diagnosis and localization of the primary hepatocarcinoma that supersonic wave is diagnosed easily and simply to handle, do not there are not wound, resolution capability. And because it is cheap, diagnose that makes it become and check the first-selected method of hepatocarcinoma at present fast, it is difficult to distinguish that the shortcoming is smaller than focus of one centimetre, the accuracy rate of diagnosis can be more than 90%. Colored Doppler checks primary hepatocarcinoma, because the hepatocarcinoma blood is transported abundantly, it is extremely apt to reveal the blood flow of artery on the lump inside or edge. The peripheral blood flow is the kind of colored basket very, it is obvious the artery sometimes and get deeply to tumour, and further branch. 2,CT checks CT and checks the offering an explanation rate high, can find less tumour, there is practical value on diagnosis of hepatocarcinoma. The shortcoming is to cost an arm and a leg. CT is that the use X-ray scans human body, makes information, the reconstruction picture dealt with and won by the electronic computer. CT hepatocarcinoma behaves and keeps the same with pathologic shape on the whole, it is flat to sweep as low density more, a few, in order to wait for the density or mix the density, appearance abnormality takes the form of sphere or tubercle, the border is fuzzy. Strengthen and scan and is shown as the low density district slightly narrows, it is comparatively known that the realm makes. The intersection of lump and the intersection of centre and position because tumour organize necrosis bag out of shape to succeed the very much low density district often. Lump can the single shot even may occur frequently. Difficult to find to filling the air hepatocarcinoma early CT. 3,The nuclear magnetic resonance is checked: Check the new valuable diagnostic method of hepatocarcinoma in nuclear magnetic resonance, determine the nature with CT looks harm - -About 95%, also cost an arm and a leg. Hepatocarcinoma and tubercle generally present the low signal as what was had of T1 weighting, the high signal as what was had of T2 weighting. Characteristic for appear thick guide or the intersection of blood supply and the empty signal shedsing vascular in the focus image its, this signal has arteriovenous shunt to take shape to brief on. In addition, it is very sensitive that MRI shifts the lymph node behind liver door and peritoneum, reveals. Go ahead of the rest generally at present Ultrasonography B check, discover the problems nuclear magnetic resonance reexamine determine with or CT again.
(3) The liver can be punctured, examined alive under the circumstances that Ultrasonography B or isotope make a reservation while wearing the biopsy, positive rate 76.1%- 92.3% , In addition it release ascites find out cancer cell, shift lymph node, examine while being living, cut open belly ascertain, fetch biopsy. Here add one point, the intersection of patient and Chen in the book this, surgery slice, examine, find cancer cell either while being alive ascertain, those years, but verify clinically he had already belonged to later period hepatocarcinoma at that time.
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