Vaccine the hottest keyword of AIDS of 09 years

Vaccine, the hottest keyword of AIDS of 09 years
In view of HIV's complicated variation, once the Nobel Prize winners prophesied pessimistically: The mankind can not find vaccine of AIDS within 25 years, " L And can not probably find this kind of vaccine forever " .
In 2009, will make quite a lot of persons feel the one filled with exultation is, U.S.A. cooperates with Thailand and researches and develops a kind of union vaccine, verified can prevent and cure AIDS. However, rounding this vaccine, more professional personnel have expressed the worry, even suspect - -
Begin to show from despair to dawn
American former president Bill and Clinton proposed, should develop effective AIDS vaccine within 8- 10 years in 1997. Hereafter, though U.S.A. and countries all over the world were racing against time and falling over each other to develop vaccine of AIDS, but been producing effects all the time not big.
When the whole world falls into vaccine of AIDS and researches and develops hopeless depressing atmosphere, perhaps a result of study of U.S.A. and Thailand lets people see dawn. The American, safe cooperation of both sides, research and develop a kind of union vaccine, is called three Thailand (Thai stage, have another name called RV144) ,Can be infected with the risk reducing 31.2% of HIV of the human body. World Health Organization with the intersection of the United Nations and AIDS plan, say great affirmation and optimism to this research by administration, think this experimental result is defective virus (HIV) of human immunity Vaccine research " L Pour into the new hope " ,The result of new vaccine is encouraging. Main and responsible scientist of Chinese origin Dr. Jiao Jun says in this research, new vaccine really may prevent and cure AIDS.
This research costs nearly 1.05 A hundred million dollars . So-called the intersection of union and vaccine jointly use and test ALVAC vaccine failing in the past ' Comparable to Philippine Pasteur Company of the promise to produce by France) With AIDSVAX vaccine (developed by U.S.A. VAXGEN Company) ,The purpose is accomplishing " L Start and strengthen the tactics " . ALVAC stimulates the human immune system first, let it start and attack HIV; But AIDSVAX serves as the secondary attack, in order to strengthen immunoreaction. Vaccine ALVAC of HIV uses a kind of canary's small pox and virus (canarypox) Bird flu virus, through transforming as carrier, it contain three kinds of parts genetics of HIV virus, but will not cause people to be ill. But AIDSVAX vaccine contains a certain albumen that surface of HIV has been transformed by genetic engineering, will not cause people to be ill too.
Unite vaccine, begin, test on will it be October 2003, it tests targets to be in 1.6 more than age Wan on Thailand choose in from 18 year old to 30 -year-old wish person. The HIV test of the people is negative, and their infection risk is equal to the ordinary crowd's average level. The volunteer is divided into two groups, one group injects and unites vaccine (the injection four stitches of ALVAC and two stitches of AIDSVAX within 6 months) ,Another organize ' Control group) Only inject placeboes. Until the test is over, the volunteer did not know whether to inject true vaccine by oneself. The result reveals, in 8197 volunteers who accept vaccine injection, 51 people have been infected with HIV, have 74 people who infect HIV in 8198 people of the control group. Researchers think, this difference has meaning of statistics, vaccine has function of resisting AIDS, can reduce HIV infection rate and exceed 31%.
The sound queried is constant
However, according to the idea of the prevention from suffering from the diseases, a kind of vaccine should have 80% of the prevention results that can be called success, can sanction producing and listing also. However, the difficulty studied because of vaccine of AIDS, researchers think now, even some little results, it is a kind of success for AIDS preventing and controlling. Certainly 30% of the prevention results are much better than zero. Such a result increase, infect the case speech to the whole world newly by 7500 HIVs every day, also a kind of fairly good protection.
However, subsequently more rigorous scientific analysis makes this vaccine test have 31% of the protective statements that are queried strongly. In U.S.A. at the end of October of 2009>Have announced the intact report of vaccine test of this AIDS on websites. The report thinks, if analyze with more rigorous scientific standard, only 26% of vaccine validity this time. This rate has already been lower than the number value of the statistics meaning in fact, has meant too there is not protective action in fact in vaccine, like result of placebo, or the same with inoculating vaccine.
Initial analysis has not included 7 patients, they have already been infected with AIDS before beginning the test. If analyze, only 12450 people have participated in and tested from the beginning to the end from integrality, namely intact vaccine inoculation or invalid the intersection of comfort and pharmaceutical, inject 6 stitch vaccine or 6 stitch comfort pharmaceutical altogether within 6 months. So as to analyze, then only 26.4% of result of vaccine. Another analysis is to include those 7 7 people infected with AIDS before vaccine inoculation, also obtained only 26.2% of validity of this kind of vaccine.


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