The vaccine immunization campaign unusually reacts and monitors and deal with

The vaccine immunization campaign unusually reacts and monitors and deal with
First, immunization campaign unusual reaction basic conception
Vaccine inoculation is prevented, controlled and directed against the effective measure of infectious disease, but any kind of vaccine is not absolutely safe. With the improvement of the inoculating rate effectively of a kind of vaccine, vaccine is directed against the decline of the morbidity of infectious disease, the response after vaccine inoculation arouses great concern from people.
(1) Definition unusually reflected in suspected immunization campaign
Monitor in order to unusually reflect the immunization campaign, find and deal with the immunization campaign and unusually react in time, define used for monitoring suspected immunization campaign react, define unusually in " the norm ", it means what happens after or inoculates in the course of immunization campaign perhaps leads to the fact that is damaged by the organism histoorgan, function of the persons who plant, and suspect the response related to immunization campaign.
This definition includes the content of 3 respects:
1.Emergence and immunization campaign of the case exist for rational time, must happen after or inoculate in the course of immunization campaign.
2.Certain histoorgan or damage of function happens by the organism of persons who plant.
3.Meet and examine a doctor to suspect the emergence of the case relates to immunization campaign during visit in case.
On the contrary, the case with one of the following situations is not that the suspected immunization campaign unusually reacts: Happen before the immunization campaign; Or the histoorgan or function has not taken place and damage the consequence after the immunization campaign; Or meet and examine a doctor and totally get rid of it with immunization campaign relation while going to a doctor.
(2) Classification unusually reflected in suspected immunization campaign
The suspected immunization campaign unusually reacts after investigating and analysing, divide for the following types (Fig. 1) according to its reason .
1.Bad reaction
Inoculate the bad reaction or side reaction after vaccine, mean the persons who are planted after vaccine inoculation, response harmful to organism related to immunization campaign taking place while or after the organism produces beneficial immunoreaction. The bad reaction of immunization campaign can be divided into general response and unusually reflected 2 kinds.
(1)The general response refers to the response caused by own characteristic of vaccine, determined by inherent property of vaccine, its clinical manifestation and intensity vary from vaccine. The response intensity is confined to certain limit, it is slightly heavy to react because of the organism difference except one or two people, mostly slight; Reaction process rather than permanent one; The response will not cause the irrecoverable histoorgan to damage, or the obstacle functionally (but except some cicatrix of Bacillus Calmette-Guerin) ; Without sequela, this is an inherent characteristic of general response.
(2)React, refer to, use qualified vaccine probability not taken place very much low after not implementing norm inoculate unusually, to caused the damage by organism histoorgan, function,etc. of the persons who planting, each side correlated to incident does not have a medicines bad reaction of fault.
The definition unusually reflected in immunization campaign includes the content of 3 respects:
Use qualified vaccine: Vaccine used should be accredited registering by the pharmaceuticals administration department in the country; Assay the organization and criticize quality inspection through national medicines, get " the biologicals criticize and issue the certificate of quality "; The circulation accords with the regulations of " regulations "; Vaccine refrigerates warehousing and transportation and fulfils requirements, use within term of validity.
Implement regulatory operation: Inoculate unit and staff member and pass the qualification certification of health authority; According to " norm "
Demand to implement the immunization campaign, and make sure to inject safely.
Lead to the fact that is damaged by organism histoorgan, function,etc. of the persons who plant: To damaged and appraised by organism histoorgan, function,etc. of the persons who planting.


2.Accident
Mean because vaccine is off quality, or because violate the behaviour of immunization campaign while the immunization campaign implement, immune procedure, vaccine use the guideline, inoculate the scheme etc. to lead to the fact that is damaged by the organism histoorgan, function of the persons who plant. Its reason including vaccine immunization campaign off quality that happens implements 2 respects of mistake, not only may lead to the fact directly that is damaged by the health of the persons who plant but also may increase and take place general response and danger that unusually reacts of immunization campaign.
3.Coincidence disease
The strict one says that can be divided into coincidence, brought out and aggravated 3 kinds of situations of original disease. The coincidence means that is in the incubation period or prodromal stage of a certain disease during inoculation sharp the persons who plant, the coincidence has illness coming on after inoculating; Bring out, mean, have the intersection of vaccine and whom manual stipulate inoculate the taboo card person who plant, person who plant before inoculation or guardian its offer health status of person who plant and inoculate taboo situation accurately, original disease acute recuring or physiological course of influence of the persons who are planted after inoculating; It means that is suffered from chronic disease originally, cause after the immunization campaign immediately aggravating or acute recuring by the persons who plant to aggravate, through investigating that there are persons who concern certainly in verifying and immunization campaign. Aggravate one that original disease too be brought out in fact, but clinical symptom and physical sign are more serious. There is not any relation with vaccine inoculation in the coincidence, namely no matter inoculating vaccine will have illness coming on; There are direct or indirect relations with the immunization campaign to bring out and aggravate, namely does not inoculate vaccine, would not cause the recurring of the original disease or aggravate.
4.The heart reacts because of the sex
Mean it while the immunization campaign implements or because of being reacted by the individual or colony taking place in psychological factor of the persons who plant after inoculating. Heart spirit or psychological factor because of the person who reacts and plants sex is relevant, not vaccine causes.
5.Unidentified reason
The unidentified reason means the suspected immunization campaign unusually reflects the process to investigate, analyze, its reason that happens still can't be clear.
It is that a content includes the extensive concept that the suspected immunization campaign unusually reacts, happen until health cause damage person who plant after immunization campaign, can be referred to as the suspected immunization campaign and unusually react. It may belong to the abnormal state related to immunization campaign, real and react; Also may be the coupling the disease that disease or other reasons caused independent of immunization campaign. Because people lack the restrictions of the knowledge and medical science knowledge of immunization campaign, react, unusually react suspected immunization campaign that confuses with the immunization campaign unusually often.
In suspected immunization campaign is unusually concepts such as reacting, bad reaction, unusually reacting,etc., the definition epitaxy unusually reacting by the suspected immunization campaign is most extensive, but bad reaction and a relative limitation of definition that unusually reacts.
(3) Corresponding relation unusually reflected and classified with the bad incident of immunization campaign in suspected immunization campaign
WHO divide AEFI into vaccine, react, implement mistake, the intersection of coincidence and disease, inject react and unidentified the intersection of reason and 5 in the guide in " the the intersection of immunization campaign and the intersection of security and monitoring ", the corresponding relation that it and suspected immunization campaign unusually react and classify is shown in Table 1. Can find out, the suspected immunization campaign of our country unusually reflects that does not have material difference to classify with AEFI of WHO to classify.
Table 1 suspected immunization campaign unusually reacts and classifies the corresponding relation classified with the bad incident of immunization campaign


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