There will be a new method Great Britain to find that causes the gene of the epilepsy in the epilepsy treatment
According to Britain>Report British scientist find mouse lacking ATP1A3 gene might initiate serious epilepsy symptom in the brain August 4. Result of study this it issues to be here one newly >Have.And some people will maul by head, the intersection of brain and tumour, other neural disease,etc. initiate epilepsy. The scientist has been thinking all the time, most epilepsy may be caused by gene, but been failing to win confirmation all the time.The research group that British Liz neurologist Stephen and Clark of the university specially led hybridizes the normal mouse with the mouse who suffers from epilepsy, and let the normal mouse have duplication of the extra ATP1A3 gene through the genetic engineering method. Extra duplication has remedied the shortage of ATP1A3 gene, so, its offspring does not have epilepsy symptom, its enzyme that equilibrates sodium and potassium density is in normal state.Researchers claim, in mouse and the mankind, ATP1A3 gene all responsible for regulating the density of sodium and potassium in the brain. ATP1A3 gene produces an enzyme, this enzyme can regulate the density of sodium and potassium in the brain just like sodium potassium pump. The mouse which suffers from the epilepsy lacks ATP1A3 gene, enzyme turned into is active, it is not enough to equilibrate the density of sodium and potassium, so, the epilepsy of the mouse will break out regularly.Researchers have sifted and checked a lot of epilepsy patients' DNA sample, whether in order to verify the genetic defect equally to make some people suffer from the epilepsy more easily, they claim, match degree of mankind and mouse gene 99% means this gene may work in the human body.Researchers point out, in the epileptics patient, the brain is in the highly excited state, this means, when the epilepsy patient's brain is stimulated, will present the situation that the neuron discharges more easily, let epilepsy symptom be more obvious, the activity that sodium and potassium discharges influencing the neuron.The scientist says, if this research can be applied to the mankind, will contribute to finding the brand-new method to treat epilepsy. A method is that sodium potassium pump enzyme which provides the artificial synthesis for patient helps to mediate the density of sodium and potassium in the brain; Also can design medicines to activate this no longer active enzyme. (Liu Xia )With the enhancement of health consciousness, people pay more and more attention to with the life closely bound up health problem, such as the food security, medical treatment is ensured, medical information,etc., healthy life should be from understanding information begins! More excellent health information please enter : News channel
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