New problem of old medicine of a century Aspirin is although in order to pay attention to the side effect

New problem of old medicine of a century Aspirin is although in order to pay attention to the side effect
Aspirin was entered in 1899 and used clinically, age will be larger than BAIYAO (white drug) (sic) of Yunnan of China (BAIYAO (white drug) (sic) of Yunnan was formulated in 1902) ,It is old medicine of qualified a century. Except that the ones that find solve heat, diminishing inflammation, function of easing pain first, it is used for preventing and curing vascular disease of the heart brain and having a history of more than 20 years too, the intersection of U.S.A. and FDA sanction aspirin can use for, take place in heart failure patient and some apoplexy and angina pectoris patient ever on 1984.Although aspirin is good, there is a side effect
People have already known aspirin can be used for preventing and curing vascular disease of the heart brain. As to once there were having a heart attack and patient of the apoplexy histories, and the coronary heart disease patient making a definite diagnosis of iting, because the result of study obviously inclines to exceed the risk in benefit brought to patient in aspirin treatment, so use aspirin to have no objection to treat in these patients. As far back as 1985, U.S.A. hygiene at that time and Margaret, minister of people's service department? Hechler (Margaret Heckler) ,Have held a bottle of aspirin and announced: Take a slice of aspirin every day, contribute to preventing the second heart failure.
But break out in the history in there are not heart disease and heart brain blood vessel incidenting, the crowd who has this kind of risk, whether should take aspirin conventionally, but been having objection all the time. In this case, do not benefit so obvious as in the patient of the vascular disease of original heart brain, benefited and no longer leant to one side with the risk, then the dispute appeared. It is that it resists the blood platelet to gather function that aspirin is used for preventing and curing vascular mechanism of the disease of the heart brain, thus prevent the thrombosis in the blood vessel. We know the function of the blood platelet is styptic, it is a step in the styptic course that the blood platelet is gathered, aspirin blocks this course, will increase the risk bleeding.
The present guide of cardiovascular prevention and cure of disease recommends using aspirin for the first class prevention of the intermediate coronary heart disease risk crowd, even if recommend already knowing to have certain coronary heart disease risk people not suffering from this disease yet to prevent (the concept of tertiary prevention has been in modern medical science through taking aspirin: It has no disease to prevent disease that first grade is prevented; Second prevention refers to the discovery in early days of disease, diagnoses in early days, treats in early days; Tertiary prevention refers to back-end treatment of disease and recovery) . On but May 30 this year, publish a research thesis on Britain's famous medical science " lancet " magazine, research this use for disease first class prevention and second clinical trial that prevent from of cardiovascular vessel, go on comprehensive analysis to multiple relevant aspirin. The result of study points out, at the time of the first class prevention used for vascular disease of the heart brain of aspirin, can make it is myocardium infarction of the mortality that reduce by 1/5, but can't lower the risk of apoplexy notably; But in bad reaction, the risk bleeding has increased by 1/3. So, the author of this thesis thinks, to the patient not be in the mood for vascular disease of the brain, should not recommend using aspirin as and preventing from using medicine.
As to this, spokesman of American heart association, the cardiovascular disease expert Gerad? Fletcher (Gerald Fletcher) The doctor has different opinions. He think present guide reasonable, low dose of aspirin little having, having a heart attack crowding of the risk in risk to bleeding, the benefit brought is greater than the risk.Peple of one mind fall into the same group, medicine should be with each too
But no matter agree in using aspirin to be used in first class prevention, two experts both think, prevent vascular disease of the heart brain, the focal point should be put in controlling blood pressure and cholesterol, control these dangerous factor, come on and confront with each other the blood platelet and assemble more meaningfully with aspirin than simply. To hypertension patient, it is an absolute principle that it is up to standard that blood pressure is controlled; And to raised person of cholesterol, the ones that should consider first are to use his spit of fland to lower lipoprotein medicine, but not anxious to use aspirin.
In view of the existence of these different opinions, as to every concrete patient, may should detailed conditions make a concrete analysis of, weigh the advantage and disadvantages managing into doctoring, to determine whether to need to use aspirin. Two respects expert opinion agreed and objected to synthetically, can find out, the focus of this dispute lies in: Take place the intersection of heart and the intersection of brain and vascular disease person, take aspirin, lead to the fact risk and take aspirin, result in take place the intersection of heart and the intersection of brain and vascular risk of disease that bleed, every one is bigger. The clinical research that perhaps will come can further subdivide this crowd, find out who are suitable for using aspirin to carry on first class prevention from it, who are unsuitable.
In addition, as to saying with medicine, it is more economic, more simple and more convenient routes to prevent heart cerebrovascular diseases by changing the life style, its result is quite prominent too at the same time. Peking University the intersection of the People's Hospital and Hu Da one professor, heart of centre think cardiovascular the intersection of disease and first class prevention should stress, put emphasis on, change life style, our country should especially stress that put emphasis on accusing of cigarettes at the present stage.
The opinion on the expert, perhaps we should treat like this: As to the thing that a certain medicine could be suitable for a certain particular crowd, even better expert, his view is not convincing as an large-scale clinical result of study of high quality too; But on the other hand we should even see, the clinical research and clinic diagnosis guide compiled on the basis of they although has guidance functions, but may not necessarily contain all patients, may not necessarily take the concrete difference between every patient into account either, in this way, need the expert of clinical medicine on the basis of latest result of study, use his theory knowledge and practical experience to judge whether some concrete patient can benefit to use a certain medicine. This is complexity of medical science, exactly what the sophisticated doctor's value is all about too.
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