Man contraceptive: Era male health care of _ of male contraception
Reproduction and health fair that hold in the Beijing Exhibition Centre this month are regarded as research of China's healthy reproduction and first show in the world of achievement, have given people too many hopes. However, male contraceptive of hot research object among them has not appeared in people's visual field yet yet.
"Though many scientists of countries all over the world are devoted to the research of male contraceptive and made many progress in the research field, but up till now, contraception medicines of no kinds of ripe, market-based men worldwide. "
Study the prerequisite: Over half men would like to take contraceptives
The traditional idea formed for a long time, the feeling given to somebody seems that it is women's " patent " to practise contraception . Also just because of this, women have made too many sacrifices to this. In medical science theoretically, no one " must " It is natural " The patent " . Right and obligation are equal for anyone, it is the same to practise contraception.
Take the hormone method to make men practise contraception, this is a main subject of the research field in recent years, the latest research results demonstrate the possibility to come out in inner male contraception tablet from 5 to 10 in the future soon too at the same time. In order to foresee the operating position of male contraceptive, researchers from Edinburg, Shanghai, Hong Kong and Cape Town, have carried on two investigations to 4000 men and women of four cities. The content includes: Would the man like to use this kind of hormone method to practise contraception? Woman believe in the intersection of sex and companion of them wipe out practise contraception block really? In 2000 among the men investigated, majority welcome like this new method, 2/3 of the people say that once can get, they will use this kind of medicine. The digital display of Hong Kong, half the men express willingness to take male contraceptive.
Study the current situation: No research turns into products
Like nearly all scientific research, though there is no great breakthrough progress during decades in the research of male contraceptive, but the research competitions of the countries all over the world are like a raging fire.
According to the introduction of human reproduction and an article of " the mankind bears "'s of periodical which the embryo learns of Europe last year, the scientist of Edinburgh University says, they and Chinese scientist has tested research for a long time, develop a male contraceptive together. It proves clinically, 100% of such male contraceptive are effective and not having side effect to pass.
Medicine this to can prevent the intersection of man and hormone and testosterone that sexual desire fail from make by one synthetic steroids, stop producing sperms and achieve the goal of practising contraception through releasing hormone on the blood. Go on drug test as long as several months to 30 man each in Edinburg and the intersection of China and Shanghai. According to biological centre of reproduction of Edinburgh University, the man who takes medicine all stop producing sperms, but there are no side effects such as fat adenitis, hypertension etc.. Contraceptive of man that tested in the past all have the above-mentioned side effect. This kind of contraceptive can make to prevent hormone which produce the sperm from entering blood and contributing.
Besides Edinburg, are developing one to only need contraception vaccine injected in Strathclyde university of Glasgow once every year too, in order to control sperm grow up, make the intersection of sperm and unable development to can make maturity stage that woman become pregnant. And British Glaxo Wellcome biomedical research institute attempts to pass the chemical method, make it gush out muscle to stock seminal fluid to be unable to move about sperm not to responsible for. The expert of Sydney Concord hospital of Australia adds the ranks of developing male contraceptive too, its injection type medicine developed, only need to inject once every three weeks in theory, can reduce the quantity of the male sperm effectively, reach the contraception result. And another kind of utilize chemical glue stop up the intersection of man and contraception of spermatic duct, expect that can emerge in 10 years. It is that the glue can be dissolved by the chemical material than the place where the vasoligation has the advantage even more, resume the reproduction function at any time.
On March 2 this year, the academic magazine U.S.A.'s " science " of international authority is with " an antibacterial peptide gene in the big mouse's reproductive system " Have issued a great achievement of the scientist of our country for the question. The scientist of our country makes the great breakthrough in the gene studies of reproductive system: From the big mouse's epididymis (a crooked slender pipeline which connects testis and spermatic duct) for the first time in the world Succeed in cloning in skin cells to a peculiar new gene that expressed on the head, and polypeptide that observes this gene encodes has antibacterial functions, and may relate to bearing. This new gene of antibacterial peptide in nature is expected to develop into the peculiar new medicine to treat the male epididymis inflammation, in order to reduce the emergence of the male infertility, may become a new contraceptive used for man too.
It is difficult in difficult: The high repayment of investment is slow
Professor Chen says, male contraceptive is studied, the reason why lagged behind women contraceptive for a long time, a very important reason is the difference of men and women's reproductive system.
Theoretically, it realizes meanses that practises contraception to be to prevent sperm and combination of ovum only practising contraception a most simple one. Looking from male reproduction characteristic, normal men produce about 1000 sperms every minute, produce several million sperms per month, and the cycle of surviving is long, generally all on 60 to 70 days; And women only arrange the ovum once every month, the onset of ovulation only discharge an ovum each time. Look from medical angle, control or deal with an ovum certainly is more easily than to deal with several million sperms effectively. Really, only 1 of miss ratio of contraceptive for ladies. Another difficulty is people's understanding question. Professor Chen say, finally male contraceptive has great space of market (mean how much male approval there is) ,Topic of drawing a conclusion in inconvenience that this is very one. Though many survey reports demonstrate its broad market prospect, an undeniable fact is: Women birth-control drugs even in through how much year today popularize, women take just about 3% of contraceptive proportion. Men are hard to more say.
Moreover, say, the thinking old habit for a long time makes many men very difficult to accept the concept of male contraceptive just as this text in the front. Even if the surface is done quite magnanimously, but the man at heart " self-respect " But let them produce resisting and shame sense to contraceptive more or less.
Perhaps for research scientist of decades like Professor Chen, all these are not enough to form too great obstacle. But what made them feel very awkward is, they often feel " unable to do what one wants very much to do " . Though the country knows and relatively pays attention to on male contraceptive in recent years, but too little on fund input. A lot of of their scientific research tasks mainly depend on the producer in, the investment of the company or supporting, but because study the long periodicity, the payback is difficult to predict whether a lot of companies, producers have been holding the wait-and-see attitude all the time or not. It is difficult more or less for this to be accepted by people.
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